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February 2000 Meeting

1999 ACS Award for
Creative Work in Synthetic Chemistry
sponsored by
Aldrich Chemical Company


RESEARCH AT THE CHEMISTRY-BIOLOGY INTERFACE

Awardee

Dale L. Boger

Richard & Alice Cramer Professor of Chemistry
Scripps Research Institute
La Jolla, CA



Thursday, February 24, 2000
Kenwood Inn
University of Wisconsin - Milwaukee
2300 Kenwood Blvd.
Milwaukee, WI
(in the UWM Union on the 3rd floor)

DIRECTIONS


6:00 PM - Social Hour
7:00 PM - Dinner
8:00 PM - Meeting and Program
Lecture will be held in Room N146, School of Business

Buffet Dinner: (Prices include tax and gratuity)
  • Roast Beef aus jus.
  • Baked Cod Almandine with Lemon Butter.
  • Vegetarian option available if placed at time of reservation.
Members/Guests .... $17.00
Chemistry Students .... $8.00

For dinner reservations, please call
Joanne Ballini/Marquette University
288-3515

by
Friday, February 17, 2000
All are welcome.
Come and hear the speaker without attending the dinner.

ABSTRACT

The research interests of our group include the total synthesis of biologically active natural products, the development of new synthetic methods, heterocyclic chemistry, bioorganic and medicinal chemistry, combinatorial chemistry, the study of DNA-agent interactions, and the chemistry of antitumor antibiotics. We place a special emphasis on investigations to define the structure-function relationships of natural or designed agents in efforts to understand the origin of their biological properties.

Central to such studies are the development of dependable synthetic strategies and the advent of new synthetic methodology to permit the preparation of the natural products, key partial structures, and analogs incorporating deep-seated structural changes. The resulting efforts have reduced many difficult or intractable synthetic challenges to manageable problems providing an approach not only to the natural product but one capable of simple extrapolation to a series of structural analogs as well. In our own efforts this has provided the opportunity to fully explore the origin of the natural products properties and to devise agents with improved selectivity and efficacy.

BIOGRAPHICAL SKETCH

Dale Boger received a B.Sc. degree in chemistry from the University of Kansas, Lawrence, and a Ph.D. degree in chemistry from Harvard University in 1980. He served on the faculties of the University of Kansas and Purdue University. In 1991, he joined Scripps Research Institute, La Jolla, Calif., where he is presently Richard & Alice Cramer Professor of Chemistry. Previous awards and recognitions include a Searle Scholar Award, an Alfred P. Sloan Fellowsip, an ACS Arthur C. Cope Scholar Award, and the 1997 Katritzsky Award in Heterocyclic Chemistry of the International Society of Heterocyclic Chemistry. He is the 1999 recipient of the ACS Award for Creative Work in Synthetic Organic Chemistry, sponsored by Aldrich Chemical Co.

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December 30, 1999