Symposium - Protein Structure and Function, 2006 GLRM

FEATURED SYMPOSIUM

Sponsored by ACS Division of Biological Chemistry

Protein Structure and Function

Co-Chair: Daniel Sem (Marquette University) - daniel.sem@mu.edu
Co-Chair: Graham Moran (University of Wisconsin-Milwaukee) - moran@uwm.edu

Three - Half Day Sessions

Invited Speakers

Session 1: Structure and Dynamics

Thursday AM, June 1, 2006

Click Here for the Schedule and Abstracts

Protein disorder revealed by structural genomics and NMR

Brian F. Volkman

Biochemistry & CESG
Medical College of Wisconsin

The bZIP Domains of Eukaryotic Transcription Factors:
Their Dimerization and Specific Interaction with DNA

Youngchang Kim

Structural Biology Center & Midwest Center for Structural Genomics
Argonne National Laboratory

Modulating p27 Function Through Phosphorylation;
Intrinsic Protein Disorder Enables a Two-step Oncogenic
Mechanism Leading to Destruction

Richard Kriwacki

Structural Biology
St. Jude's Children's Research Hospital

Crystalline Enzymology: Trapping Catalytic
Intermediates of Methylamine Dehydrogenase

Carrie Wilmot

Biochemistry, Molecular Biology & Biophysics
University of Minnesota

Structure, Dynamics and Ligand Interactions of Raf Kinase Inhibitor
Protein (RKIP)

Shohei Koide

Biochemistry and Molecular Biology
University of Chicago

Molecular Structure of Saccharomyces Cerevisiae Gal1p
- a Bifunctional Galactokinase and Transcriptional Inducer

Hazel Holden

Biochemistry
University Wisconsin-Madison

Session 2: Enzymology

Thursday PM, June 1, 2006

Click Here for the Schedule and Abstracts

E Unum Pluribus:
The Common Active Sites of Flavoenzymes in Pyrimidine
Metabolism Choose Different Mechanisms - Sometimes

Bruce Palfey

Biological Chemistry
University of Michigan

Model for the Protein-protein Interactions of Diiron
Desaturase with Acyl-acp and Ferredoxin

Brian Fox

Biochemistry
University Wisconsin-Madison

Mechanisms of Reversible Protein Acetylation

John Denu

Biomolecular Chemistry
University Wisconsin-Madison

Second Sphere Effects in Aromatic Ring Cleaving Dioxygenases:
Reaction Cycle Dynamics and Origins of Specificity

John Lipscomb

Molecular Biology & Biophysics
University of Minnesota

Mechanism and Motion in Bacterial Alginate Biosynthesis

Peter Tipton

Biochemistry
University of Missouri-Columbia

Nucleophile Isotope Effects on Enzyme Catalyzed Reactions

Vernon Anderson

Biochemistry
Case Western Reserve University

Session 3: Methods in Biochemistry and Chemical Biology

Friday AM, June 2, 2006

Click Here for the Schedule and Abstracts

Characterizing Drug Resistance in Beta-lactamases
by Raman Crystallography

Paul R. Carey

Biochemistry
Case Western Reserve University

Structure-based Drug Design for DPP-IV Inhibition

Kenton Longenecker

Abbott Laboratories

Cognate Site Identification: Comprehensive Analysis
of DNA-ligand Recognition

Aseem Z. Ansari

Biochemistry
University Wisconsin-Madison

Interrogating Protein Druggability Using Chemical Libraries

Phillip Hajduk

NMR-Based Screening
Abbott Laboratories

Chemical Probes for Studying Protein-Ligand Interactions
in vitro and in vivo

Daniel Sem

Chemistry
Marquette University

Dissecting the Replication Fidelity of DNA Polymerases
into Binding and Chemical Contributions

Jan Florián

Chemistry
Loyola University